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Global protein turnover quantification in Escherichia coli reveals cytoplasmic recycling under...
Nature· 3 days agoGupta, Johnson et al. quantify the turnover rates of ~3200 E. coli proteins, demonstrating that cytoplasmic proteins are recycled when nitrogen is limited and that protein degradation rates are generally uncoupled from cell division rates.
Computational screening combined with well-tempered metadynamics simulations identifies potential...
Nature· 3 days agoType-II transmembrane serine proteases are effective pharmacological targets for host defence against viral entry and in certain cancer cell progressions. These serine proteases cleave viral ...
The AKT inhibitor AZD5363 elicits synthetic lethality in ARID1A-deficient gastric cancer cells via...
Nature· 3 days agoGastric cancer (GC) is a deadly disease with poor overall survival and limited therapeutic options. Genetic alterations such as mutations and/or deletions in chromatin remodeling gene AT-rich ...
A shameful system of research - Nature Medicine
Nature· 3 days agoA shameful system of research. Nat Med 16 , 633 (2010). https://doi.org/10.1038/nm0610-633...
Committee planned to weigh misconduct in Australia - Nature Medicine
Nature· 3 days agoCommittee planned to weigh misconduct in Australia. Nat Med 16 , 620 (2010...
Diabetes drug woes spell trouble for the entire drug family - Nature Medicine
Nature· 3 days agoDiabetes drug woes spell trouble for the entire drug family. Nat Med 16 , 614 (2010...
Stem cell decision could rewrite rules of patentability - Nature Medicine
Nature· 3 days agoStem cell decision could rewrite rules of patentability. Nat Med 16 , 619 (2010...
Beyond high school, 'colleges' teach medical marijuana - Nature Medicine
Nature· 3 days agoBeyond high school, 'colleges' teach medical marijuana. Nat Med 16 , 621 (2010). https://doi...
Four years on, clinical partnerships program proves worth - Nature Medicine
Nature· 3 days agoFour years on, clinical partnerships program proves worth. Nat Med 16 , 612 (2010). https...
Industry looks to buck bias in emerging 'adaptive' designs - Nature Medicine
Nature· 3 days agoIndustry looks to buck bias in emerging 'adaptive' designs. Nat Med 16 , 619 (2010...