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Idience: developing selective and potent PARP inhibitor IDX-1197 for solid tumors
Nature· 1 day agoThe first wave of PARP inhibitors has improved outcomes in people with a variety of solid tumors. The company plans to target homologous recombination repair-proficient patients ...
Glycostem launches pivotal oncology trial with evolved naked natural killer cells
Nature· 1 day agoGlycostem’s pivotal trial is planned to start in late 2020 and will involve five European countries, eight clinical trial centers and 33 patients with minimal residual disease (MRD) positive ...
In This Issue - Nature Reviews Molecular Cell Biology
Nature· 1 day agoPost-translational modifications have important roles in regulating protein function. Histone proteins, for example, are covalently modified on amino-acid residues in their tail regions, and ...
Early treatment of COVID-19 with anakinra guided by soluble urokinase plasminogen receptor plasma...
Nature· 1 day agoThe SAVE-MORE phase 3 study demonstrates the efficacy of anakinra, an IL-1α/β inhibitor, in patients with COVID-19 and high serum levels of soluble plasminogen activator receptor.
Here’s what it takes to bake the shift to GenAI
TechRadar· 1 day agoEnterprises, which today are at the very early stages of their GenAI journeys, must work in new ways and design GenAI applications with enterprise...
Trials of first-in-class bioartificial liver indicate potential
Nature· 1 day agoLiver failure, which can start suddenly or develop slowly, has a high mortality risk because of the swift onset of hepatocellular dysfunction. At least 30,000 patients in the USA and in Europe ...
A model to predict the outcome of the bilharzial bladder cancer patient after radical cystectomy -...
Nature· 1 day agoThe aim of the present study was to evaluate the prognostic factors of bilharzial bladder cancer treated by radical cystectomy: good prognosis is defined as a survival of ...
Mild cognitive impairment—a confused concept? - Nature Reviews Neurology
Nature· 1 day agoDebates about disease boundaries are not new, and they remain an essential aspect of the relationship between medicine and society. The establishment of the boundaries of Alzheimer's disease ...
ResponderID: the future of predictive biomarker discovery is now
Nature· 1 day agoThe promise of targeted cancer therapies relies on ensuring that they reach the right patients: those with the tumor-associated biological changes targeted by a given therapeutic. Achieving ...
Council Post: Why Good Judgment Is Getting Harder: How The Best Survive
Forbes· 1 day agoIt’s human decision risk triggered by our tendency to tune out and disregard who and what really...
