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AANAT1 regulates insect midgut detoxification through the ROS/CncC pathway - Communications Biology
Nature· 4 days agoArylalkylamine Nacetyltransferase 1 regulates the insect intestinal detoxification process through modulation of the reactive oxygen species-activated transcription factors pathway.
Kinetic features dictate sensorimotor alignment in the superior colliculus - Nature
Nature· 4 days agoMotor units in the superior colliculus of mice exhibit poorly defined representation of static visual fields and instead rely largely on kinetic visual features to link visual inputs to behavioural outcomes.
Mammalian cell display with automated oligo design and library assembly allows for rapid residue...
Nature· 4 days agoUsing a new method for rapid, residue-level epitope determination combining flow cytometry and surface displayed alanine substitution variants the authors determined the epitopes of three new antibodies binding the SARS-CoV-2 Spike protein.
NBS1 lactylation is required for efficient DNA repair and chemotherapy resistance - Nature
Nature· 4 days agoLactylation of NBS1 by TIP60 promotes homologous recombination-driven DNA repair and resistance to chemotherapy in cancer cells and links altered cancer cell metabolism to increase genome stability.
Second drug that slows Alzheimer's approved for use in USA
Liverpool Echo via Yahoo News UK· 4 days ago-Credit: (Image: Getty) US officials have approved a second Alzheimer’s drug that can modestly slow...
Tackling Hard-To-Treat Tumors
Forbes· 4 days agoOne of the ways researchers are trying to address this problem is by disarming the tumor’s defenses against the immune system. This article describes one such effort: a novel antibody ...
FDA Approves Second Alzheimer’s Drug after Trial Shows it Can Slow Disease by 35%
The Daily Beast via Yahoo News UK· 4 days agoThe Federal Drug Administration gave the go-ahead to a second Alzheimer’s treatment Tuesday after a...
Is Royalty Pharma plc (RPRX) a Good Stock to Buy Now?
Insider Monkey via Yahoo Finance UK· 4 days agoWe recently compiled a list of the 10 Best Undervalued Stocks To Buy Now. In this article, we are...
FDA approves second Alzheimer’s drug that can slow onset of disease
The Guardian· 4 days agoFederal health authorities on Tuesday gave approval to an experimental new drug that has shown to delay the onset of Alzheimer’s disease in trials. Donanemab, manufactured by Eli Lilly, is the ...
FDA approves donanemab, Eli Lilly’s treatment for early Alzheimer’s disease | CNN
CNN.com· 4 days agoThe US Food and Drug Administration on Tuesday approved donanemab, a monoclonal antibody designed to...