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Genomic sequencing reveals convergent adaptation during experimental evolution in two budding yeast...
Nature· 7 hours agoIn this study, the authors retrieve frozen stocks of the K. lactis lineages and reconstruct the evolutionary dynamics of parallel lineages at the genetic level with high throughput sequencing
A CRISPR activation screen identifies FBXO22 supporting targeted protein degradation - Nature...
Nature· 3 days agoBasu et al. report a clustered regularly interspaced short palindromic repeats (CRISPR)-based transcriptional activation screen method for the discovery of E3 ligases suitable for targeted protein ...
Low-dose ionizing radiation generates a hormetic response to modify lipid metabolism in Chlorella...
Nature· 1 day agoNon-toxic doses of ionizing radiation can rapidly induce increased lipid biosynthesis in green microalgae, mediated by transcriptional changes, without affecting cell viability or biomass production.
Integrative analysis of genomic and epigenomic regulation reveals miRNA mediated tumor heterogeneity...
Nature· 1 day agoA miRNA multi-omics study reveals not only mechanisms for miRNA dysregulation, but also the tumor heterogeneity and immunological diversity within low grade glioma, and presents better prognostic value than traditional molecular markers.
Embedded oxide clusters stabilize sub-2 nm Pt nanoparticles for highly durable fuel cells - Nature...
Nature· 6 days agoPt-based catalysts are state-of-the-art cathodes in fuel cells, but they experience a trade-off between activity and durability. Now a Pt nanocatalyst with embedded cobalt oxide clusters is ...
How Denisovans thrived on top of the world: mysterious ancient humans’ survival secrets revealed
Nature· 4 days agoThe cave-dwelling group hunted animals such as hyenas and hares to sustain themselves in harsh...
Ventrointermediate thalamic stimulation improves motor learning in humans - Communications Biology
Nature· 5 days agoThe authors show that ventrointermediate thalamic stimulation facilitates production of repeated sequential finger movements and modulates oscillatory cortical activity in the motor learning ...
Creative connections: the neural correlates of semantic relatedness are associated with creativity -...
Nature· 3 days agoCombining HD-EEG with connectome modeling predicts individual creative behavior from resting-state functional connectivity, highlighting the importance of optimal activation interplay across networks in creative cognition.
Small extracellular vesicles derived from microRNA-22-3p-overexpressing mesenchymal stem cells...
Nature· 4 days agoMicroRNA-22-3p enhances the protective effect of mesenchymal stem cells derived small extracellular vesicles on N-methyl-D-aspartic acid-induced retinal ganglion cell damage by regulating MAPK pathway mediated apoptosis.
Molting in early Cambrian armored lobopodians - Communications Biology
Nature· 2 days agoThis paper presents exceptionally preserved fossils from the early Cambrian that show how molting occurred in some of the very earliest arthropod relatives, a trait which enabled continuous growth in animals with hard exoskeletons.