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Haploinsufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute...
Nature· 2 days agoFamilial platelet disorder with predisposition to acute myelogenous leukaemia (FPD/AML, MIM 601399) is an autosomal dominant disorder characterized by qualitative and quantitative platelet defects ...
Modeling Autistic Features in Animals - Pediatric Research
Nature· 2 days agoSeveral known environmental risk factors for autism have been successfully established in rodents, including maternal infection and maternal valproate administration. Also under investigation ...
PTBP1 protects Y RNA from cleavage leading to its apoptosis-specific degradation - Cell Death...
Nature· 2 days agoSome RNAs such as 28S rRNA, U1 small nuclear RNA (snRNA), and Y RNAs are known to be cleaved during apoptosis. The underlying mechanism, functions, and biological significance of RNA degradation ...
Butyrate Regulates the Expression of Pathogen-Triggered IL-8 in Intestinal Epithelia - Pediatric...
Nature· 2 days agoInflammatory bowel disease (IBD) is characterized by an exaggerated immune response that involves pro-inflammatory cytokines including IL-8. Production of these pro-inflammatory cytokines is ...