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UK election: scientists welcome Labour’s landslide win
Nature· 3 days agoStruggling universities should be near the top of the new government’s agenda, say researchers.
The ACE1 secondary metabolite gene cluster is a pathogenicity factor of wheat blast fungus -...
Nature· 3 days agoMolecular analyses suggest that a blast resistance gene already defeated in rice may be revived as a durable resistance gene in wheat by targeting ACE1, a pathogenicity factor of the wheat blast fungus.
Engineered matrices reveal stiffness-mediated chemoresistance in patient-derived pancreatic cancer...
Nature· 3 days agoPatient-derived pancreatic cancer organoids grown in engineered matrices acquire chemoresistance due to the increased expression of drug efflux transporters, promoted by CD44 receptor interactions with hyaluronan in the stiffer tumoural matrix.
Publisher Correction: Mental navigation in the primate entorhinal cortex - Nature
Nature· 3 days agoCorrection to: Nature
Creative connections: the neural correlates of semantic relatedness are associated with creativity -...
Nature· 3 days agoCombining HD-EEG with connectome modeling predicts individual creative behavior from resting-state functional connectivity, highlighting the importance of optimal activation interplay across networks in creative cognition.
Structural and functional insights underlying recognition of histidine phosphotransfer protein in...
Nature· 3 days agoStudies on the phosphorelay mechanism from receiver domains of fungal hybrid histidine kinases to HPt from Chaetomium thermophilum, including from Candida albicans, suggest low affinity for complex formation and absence of a Leu-Thr switch.
A CRISPR activation screen identifies FBXO22 supporting targeted protein degradation - Nature...
Nature· 3 days agoBasu et al. report a clustered regularly interspaced short palindromic repeats (CRISPR)-based transcriptional activation screen method for the discovery of E3 ligases suitable for targeted protein ...
En quel état est l’engagement des chercheurs en sciences ? Partagez vos idées avec Nature
Nature· 3 days agoNotre première enquête mondiale auprès des responsables de groupes de recherche et d'autres...
Informed proxy consent for ancient DNA research - Communications Biology
Nature· 3 days agoEmbracing the underlying principles and processes of informed proxy consent or relational autonomy consent in human ancient DNA research can transform research.
Asymptomatic herpes simplex virus brain infection elicits cellular senescence phenotypes in the...
Nature· 3 days agoIdentification of senescence-related markers in the brain and spinal cord of mice with asymptomatic HSV-1 brain infection and animals undergoing experimental autoimmune encephalomyelitis which parallels multiple sclerosis in humans.