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Phosphorylation of PFKL regulates metabolic reprogramming in macrophages following pattern...
Nature· 1 day agoPro-inflammatory signals trigger innate immune pathways with consequential metabolic remodeling. Here authors show that a rate-limiting enzymes of glycolysis, PFKL, is directly regulated by ...
mTORC2-driven chromatin cGAS mediates chemoresistance through epigenetic reprogramming in colorectal...
Nature· 2 days agoLv, Wang, Lin, Ye et al. report that mTORC2 phosphorylates cGAS to promote its chromatin localization and SWI/SNF recruitment to regulate target gene expression, thereby mediating plasticity and chemoresistance in colorectal cancer.
Why Are Street Analysts Bullish on General Mills, Inc. (GIS) Now?
Insider Monkey via Yahoo Finance UK· 3 days agoWe recently compiled a list of the 10 Best Dividend Stocks of All Time. In this article, we are...
TRPML1 activation ameliorates lysosomal phenotypes in CLN3 deficient retinal pigment epithelial...
Nature· 3 days agoMutations in the lysosomal membrane protein CLN3 cause Juvenile Neuronal Ceroid Lipofuscinosis (JNCL). Activation of the lysosomal ion channel TRPML1 has previously been shown to be beneficial ...
General Mills, Inc. (GIS): The Best FMCG Stock To Buy Now?
Insider Monkey via Yahoo Finance UK· 5 days agoWe recently compiled a list of the 14 Best FMCG Stocks To Buy Now. In this article, we are going to...
I'm a Pro YouTuber. Here's the Video Equipment That Powers My Setup
CNET· 6 days agoWhen I launched my podcast back in 2014, I had always wanted to start my own YouTube channel to go...