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Genomic sequencing reveals convergent adaptation during experimental evolution in two budding yeast...
Nature· 14 hours agoIn this study, the authors retrieve frozen stocks of the K. lactis lineages and reconstruct the evolutionary dynamics of parallel lineages at the genetic level with high throughput sequencing
Human gastric microbiota analysis of refractory H. pylori infection - Scientific Reports
Nature· 10 hours agoH. pylori infection is gaining increasing attention, but detailed investigations into its impact on gastric microbiota remain limited. We collected gastric mucosa samples from 47 individuals ...
Low-dose ionizing radiation generates a hormetic response to modify lipid metabolism in Chlorella...
Nature· 1 day agoNon-toxic doses of ionizing radiation can rapidly induce increased lipid biosynthesis in green microalgae, mediated by transcriptional changes, without affecting cell viability or biomass production.
Integrative analysis of genomic and epigenomic regulation reveals miRNA mediated tumor heterogeneity...
Nature· 1 day agoA miRNA multi-omics study reveals not only mechanisms for miRNA dysregulation, but also the tumor heterogeneity and immunological diversity within low grade glioma, and presents better prognostic value than traditional molecular markers.
What drives mosquitoes’ bloodlust? Their hormones
Nature· 7 days agoOne hormone seems to boosts the insects’ thirst for a blood meal, while another shuts it off.
Neuroscientists must not be afraid to study religion
Nature· 6 days agoScientists interested in the brain have tended to avoid studying religion or spirituality for fear of being seen as unscientific. That needs to change.
The ACE1 secondary metabolite gene cluster is a pathogenicity factor of wheat blast fungus -...
Nature· 3 days agoMolecular analyses suggest that a blast resistance gene already defeated in rice may be revived as a durable resistance gene in wheat by targeting ACE1, a pathogenicity factor of the wheat blast fungus.
Engineered matrices reveal stiffness-mediated chemoresistance in patient-derived pancreatic cancer...
Nature· 3 days agoPatient-derived pancreatic cancer organoids grown in engineered matrices acquire chemoresistance due to the increased expression of drug efflux transporters, promoted by CD44 receptor interactions with hyaluronan in the stiffer tumoural matrix.
Mammalian cell display with automated oligo design and library assembly allows for rapid residue...
Nature· 4 days agoUsing a new method for rapid, residue-level epitope determination combining flow cytometry and surface displayed alanine substitution variants the authors determined the epitopes of three new antibodies binding the SARS-CoV-2 Spike protein.
Small extracellular vesicles derived from microRNA-22-3p-overexpressing mesenchymal stem cells...
Nature· 4 days agoMicroRNA-22-3p enhances the protective effect of mesenchymal stem cells derived small extracellular vesicles on N-methyl-D-aspartic acid-induced retinal ganglion cell damage by regulating MAPK pathway mediated apoptosis.