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Cancer vaccine approval could open floodgates - Nature Medicine
Nature· 1 day agoAfter a three-year battle with the regulatory agency and three phase 3 trials, the treatment—called Provenge, by Seattle-based Dendreon—extended median ...
In this issue - Nature Reviews Drug Discovery
Nature· 1 day agoThe renin–angiotensin system has a key role in regulating blood pressure, and is the target for several highly successful drugs for cardiovascular disease. In a 'Case history' this month, Jensen ...
From the editors - Nature Reviews Immunology
Nature· 1 day agoIn this issue, we present a series of comprehensive Review, Perspective and Comment articles on the field of therapeutic antibodies, highlighting the recent advances and future challenges for ...
From the editors - Nature Reviews Cancer
Nature· 1 day agoThere has certainly been progress on several fronts, and perhaps the most obvious would be the development of effective targeted therapies such as imatinib and trastuzumab, which have revolutionized ...
Radium Beam Therapy and High-Voltage X-Rays* - Nature
Nature· 1 day agoTHE quantity of radium now employed in the treatment of cancer, by the ‘beam’ method alone, exceeds 120 gm., with a value in excess of ...
RPN2 overexpression confers resistance to docetaxel in breast cancer - Nature Reviews Clinical...
Nature· 1 day agoHonma K et al. (2008) RPN2 gene confers docetaxel resistance in breast cancer. Docetaxel has been shown to be beneficial in the treatment
COX2 expression inhibits radiation-induced apoptosis - Nature Reviews Clinical Oncology
Nature· 1 day agoIshikawa H et al. (2006) Cyclooxygenase-2 impairs treatment effects of radiotherapy for cervical cancer by inhibition of radiation-induced apoptosis. Int J Radiat Oncol Biol ...
From the editors - Nature Reviews Cancer
Nature· 1 day agoAlthough many new targeted drugs have made it as far as the clinic and hold promise for the treatment of people already diagnosed with cancer< ...
Driving the future of CAR-T cell therapies
Nature· 1 day agoUsing a multipronged strategy, Celyad is driving the development of next-generation chimeric antigen receptor-T cell-based therapies to treat cancer.
Hypoxia Induces Alteration of Bone Morphogenetic Protein Receptor Signaling in Pulmonary Artery...
Nature· 1 day agoReduced expression of bone morphogenetic protein receptors (BMPR) has been implicated in the pathogenesis of pulmonary hypertension (PH), but changes in the intracellular signaling pathway of ...
