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A CRISPR/Cas9 screen in embryonic stem cells reveals that Mdm2 regulates totipotency exit -...
Nature· 4 days agoA CRISPR/Cas9 screen identities regulators about the transition of pluripotency to totipotency and revealed Mdm2 as a significant negative regulator of totipotency.
RNA demethylase FTO participates in malignant progression of gastric cancer by regulating...
Nature· 5 days agoRNA demethylase FTO promotes gastric cancer tumorigenesis and progression via the SP1-AURKB-ATM signaling pathway, shedding new light on the diagnoses and treatments for gastric cancer patients.
Spatially resolved imaging of human macular capillaries using adaptive optics-enhanced optical...
Nature· 2 days agoDocumenting the organization of the retinal capillaries is of importance to understand the visual consequences of vascular diseases which may differentially affect the microvascular layers.
A CRISPR activation screen identifies FBXO22 supporting targeted protein degradation - Nature...
Nature· 3 days agoBasu et al. report a clustered regularly interspaced short palindromic repeats (CRISPR)-based transcriptional activation screen method for the discovery of E3 ligases suitable for targeted protein ...
Flexible adaptation of task-positive brain networks predicts efficiency of evidence accumulation -...
Nature· 5 days agoAnalyses of fMRI data across two large samples show that people’s cognitive efficiency, as measured by a computational model, is strongly related to the degree to which brain networks involved in cognitive control adapt to task difficulty.
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Nature· 3 days agoNotre première enquête mondiale auprès des responsables de groupes de recherche et d'autres...
Publisher Correction: Multidimensional primate niche space sheds light on interspecific competition...
Nature· 2 days agoCorrection to: Communications
Ultra-detailed brain map shows neurons that encode words’ meaning
Nature· 5 days agoFor the first time, scientists identify individual brain cells linked to the linguistic essence of a...
What causes migraines? Study of ‘brain blackout’ offers clues
Nature· 3 days agoThe blinding headaches are poorly understood — a mouse study suggests that the content of spinal...
‘Chemical recycling’: 15-minute reaction turns old clothes into useful molecules
Nature· 4 days agoFast fashion creates millions of tonnes of waste each year — could clever chemistry help to tackle...