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Efficient generation of a stable CHO-K1 cell line overexpressing the human water channel aquaporin-5...
Nature· 2 days agoAquaporins (AQPs) are a family of water permeable channels expressed on the plasma membrane with AQP5 being the major channel expressed in several human tissues including salivary and lacrimal ...
Hypothalamic hormone deficiency enables physiological anorexia in ground squirrels during...
Nature· 2 days agoHibernating ground squirrels have negligible hunger despite a months-long period of food deprivation and cold exposure. Here, authors show that prolonged anorexia is enabled by inhibition of ...
A liver immune rheostat regulates CD8 T cell immunity in chronic HBV infection - Nature
Nature· 2 days agoA liver-intrinsic mechanism is presented that suppresses effective anti-hepatitis virus B responses in mice and humans by rendering virus-specific CD8 T cells refractory to activation causing loss of effector functions.
Ribonuclease 4 functions as an intestinal antimicrobial protein to maintain gut microbiota and...
Nature· 2 days agoAntimicrobial proteins have been implicated in inflammatory bowel disease (IBD). Here the authors report, using both mouse genetic models and human samples, RNASE4 as a potential antimicrobial ...
Plasmacytoid dendritic cells control homeostasis of megakaryopoiesis - Nature
Nature· 2 days agoPlasmacytoid dendritic cells monitor the bone marrow for apoptotic megakaryocytes (MKs) and deliver IFNα to the MK niche, triggering local on-demand proliferation and maturation of MK progenitors.
Immune cells phenotype and bioenergetic measures in CD4+ T cells differ between high and low feed...
Nature· 2 days agoIdentifying sources of variance that contribute to residual feed intake (RFI) can aid in improving feed efficiency. The objectives of this study were to investigate immune cells phenotype and ...
Stent coating containing a charged silane coupling agent that regulates protein adsorption to confer...
Nature· 2 days agoA self-expanding stent was constructed by laser-cutting a nickel–titanium alloy tube, which was then heat-treated to induce shape memory and electropolished to ensure a smooth surface by our ...
LRIG1 controls proliferation of adult neural stem cells by facilitating TGFβ and BMP signalling...
Nature· 2 days agoLRIG1 is an important negative regulator of cell signaling. In this study, loss of LRIG1 leads to hyperproliferation of adult neural stem cells by facilitation of TGFβ and BMP signalling pathways.
2024 Emmys Limited/Anthology Series Predictions
Variety via Yahoo News UK· 3 days agoVariety Awards Circuit section is the home for all awards news and related content throughout the year, featuring the following: the official predictions...
Yoga for beginners: how does yoga actually work?
Women's Health UK via Yahoo News· 3 days agoWhat benefits does yoga for beginners have for your body? Used to logging your reps and sets and celebrating PBs? Before we start, let’s just get this...