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The role and mechanism of action of miR-483-3p in mediating the effects of IGF-1 on human renal...
Nature· 5 days agoThis study aimed to elucidate the influence of miR-483-3p on human renal tubular epithelial cells (HK-2) under high glucose conditions and to understand its mechanism. Human proximal tubular ...
FAM122A ensures cell cycle interphase progression and checkpoint control by inhibiting B55α/PP2A...
Nature· 2 days agoFAM122A is required for timely progression through the G0/G1 transition and checkpoint integrity. Here, the authors report the mechanism by which FAM122A inhibits the major B55α/PP2A Ser/Thr ...
Humid heat environment causes anxiety-like disorder via impairing gut microbiota and bile acid...
Nature· 5 days agoHumid heat exposure has been shown to alter the gut microbiota and its metabolites. Here, the authors show that transplantation of humid heat-exposed microbiota promotes anxiety-like behaviours ...
General Election results interactive map shows the UK's new political landscape
Nottinghamshire Live via Yahoo News UK· 7 days agoReform UK had a surge in votes...
LadBaby Mum praises £3 buy that gets rid of puffiness & makes her 'glowy'
The Irish Sun· 2 days agoLadBaby Mum - aka Roxanne Hoyle - took to her Instagram Stories to share the £3.50 must-have. "Found...
6 Painting Mistakes to Avoid Next Time You Do a Refresh
Real Simple via Yahoo News· 6 days agoIn most cases, that means taping off any trim, baseboards, or doorways, using a proper primer, and...
GTPBP8 plays a role in mitoribosome formation in human mitochondria - Nature Communications
Nature· 7 days agoMultiple GTP-binding proteins (GTPBPs) aid ribosome maturation. Here, authors pinpoint GTPBP8’s involvement in human mitoribosome maturation, demonstrating its specific binding to mitoribosomal ...
PKM2 aggregation drives metabolism reprograming during aging process - Nature Communications
Nature· 3 days agoPKM2 is involved in the aging process but the mechanism remains elusive. Here, the authors show that PKM2 forms aggregates during aging and identify two small molecules which can dissolve the PKM2 aggregates and delay aging.
Shoppers praise 'holy grail' sunscreen - 3-piece set is on sale for $35
The Sun· 6 days agoAccording to the product description, it "protects against harmful UVA/UVB rays and doubles as a...
Ribonuclease 4 functions as an intestinal antimicrobial protein to maintain gut microbiota and...
Nature· 2 days agoAntimicrobial proteins have been implicated in inflammatory bowel disease (IBD). Here the authors report, using both mouse genetic models and human samples, RNASE4 as a potential antimicrobial ...