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Dietary Lecithin Protects Against Cholestatic Liver Disease in Cholic Acid–Fed Abcb4− Deficient Mice...
Nature· 6 days agoMutations in multidrug resistance 3 gene (MDR3 or ABCB4) underlie progressive familial intrahepatic cholestasis type 3 (PFIC3), a severe pediatric liver disease progressing to cirrhosis. Abcb4 ...
Molecular mechanisms of cardiotoxicity of tyrosine kinase inhibition - Nature Reviews Cancer
Nature· 6 days agoAlthough inhibition of tyrosine kinases has revolutionized cancer therapy, some of the inhibitors used have now been associated with cardiotoxicity. How does inhibition of cancer-relevant signalling ...