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Regulation of ion transport proteins by membrane phosphoinositides - Nature Reviews Neuroscience
Nature· 3 days agoMembrane phosphoinositides are important for generating key intracellular second messengers and are also able to directly regulate the activity of membrane proteins. Gamper and Shapiro discuss ...
A weak signal for strong responses: interferon-alpha/beta revisited - Nature Reviews Molecular Cell...
Nature· 3 days agoBiological systems have acquired adaptability and robustness against rapid environmental changes. A typical example is the immune system, which eradicates invading pathogens ...
See How Your Subway Service May Suffer Without Congestion Pricing
New York Times· 4 days agoExtensive cuts totaling $16.5 billion have suspended crucial repairs and upgrades to New York City’s vast transit network.
Molecular Aspects of Muscarinic Receptor Dimerization - Neuropsychopharmacology
Nature· 3 days agoThe five muscarinic acetylcholine receptors (M1–M5) are prototypical members of the superfamily of G-protein-coupled receptors (GPCRs). During the past decade, this laboratory ...
Haploinsufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute...
Nature· 3 days agoAnalysis of bone marrow or peripheral blood cells from affected FPD/AML individuals showed a decrement in megakaryocyte colony formation, demonstrating that CBFA2 dosage affects ...
Revealing new pathways for the reaction of Criegee intermediate CH2OO with SO2 - Communications...
Nature· 2 days agoCriegee intermediates such as CH2OO play an important role in tropospheric oxidation models through their reactions with atmospheric trace chemicals. Here, the authors develop a< ...
Zebrafish Clock rhythmic expression reveals independent peripheral circadian oscillators - Nature...
Nature· 3 days agoThe only vertebrate clock gene identified by mutagenesis is mouse Clock , which encodes a bHLH-PAS transcription factor. We have cloned Clock in zebrafish and show that, in ...
Climate Change Is Why I Support Rep. John Curtis (R-UT) For The U.S. Senate
Forbes· 4 days agoWilson (11.80%), and Jason Walton (5.97%). Mr... is running against Democrat Caroline Gleich, a...
Zebrafish as a Developmental Model Organism for Pediatric Research - Pediatric Research
Nature· 3 days agoZebrafish has many advantages as a model of human pediatric research. Given the physical and ethical problems with performing experiments on human patients, biomedical research ...
Accessory Atrioventricular Myocardial Pathways in Mouse Heart Development: Substrate for...
Nature· 3 days agoAtrioventricular reentry tachycardia (AVRT) requiring an accessory atrioventricular pathway (AP) is the most common type of arrhythmia in the perinatal period. The etiology of these arrhythmias ...