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A weak signal for strong responses: interferon-alpha/beta revisited - Nature Reviews Molecular Cell...
Nature· 3 days agoBiological systems have acquired adaptability and robustness against rapid environmental changes. A typical example is the immune system, which eradicates invading pathogens ...
Regulation of ion transport proteins by membrane phosphoinositides - Nature Reviews Neuroscience
Nature· 3 days agoMembrane phosphoinositides are important for generating key intracellular second messengers and are also able to directly regulate the activity of membrane proteins. Gamper and Shapiro discuss ...
Haploinsufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute...
Nature· 3 days agoAnalysis of bone marrow or peripheral blood cells from affected FPD/AML individuals showed a decrement in megakaryocyte colony formation, demonstrating that CBFA2 dosage affects ...
See How Your Subway Service May Suffer Without Congestion Pricing
New York Times· 4 days agoExtensive cuts totaling $16.5 billion have suspended crucial repairs and upgrades to New York City’s vast transit network.
Climate Change Is Why I Support Rep. John Curtis (R-UT) For The U.S. Senate
Forbes· 4 days agoWilson (11.80%), and Jason Walton (5.97%). Mr... is running against Democrat Caroline Gleich, a...
Molecular Aspects of Muscarinic Receptor Dimerization - Neuropsychopharmacology
Nature· 3 days agoThe five muscarinic acetylcholine receptors (M1–M5) are prototypical members of the superfamily of G-protein-coupled receptors (GPCRs). During the past decade, this laboratory ...
Network mechanisms of ongoing brain activity’s influence on conscious visual perception - Nature...
Nature· 7 days agoIt is not fully understood how spontaneous brain activity contributes to sensory processing. Here the authors find a number of influences of spontaneous brain activity on ...
Zebrafish as a Developmental Model Organism for Pediatric Research - Pediatric Research
Nature· 3 days agoZebrafish has many advantages as a model of human pediatric research. Given the physical and ethical problems with performing experiments on human patients, biomedical research ...
Revealing new pathways for the reaction of Criegee intermediate CH2OO with SO2 - Communications...
Nature· 2 days agoCriegee intermediates such as CH2OO play an important role in tropospheric oxidation models through their reactions with atmospheric trace chemicals. Here, the authors develop a< ...
Organic electrochemical neurons for neuromorphic perception - Nature Electronics
Nature· 7 days agoThis Perspective explores the potential of organic electrochemical neurons, which are based on organic electrochemical transistors, in the development of adaptable and biointegrable neuromorphic event-based sensing applications.